Anti-oxidant and anti-inflammatory assessment
Do you suffer in your family from:
Allergies, recurrent infections
Ocular (macular degeneration, cataract, dry eye)
Cerebral (Alzheimer's, stroke)
Vascular (tingling of the extremities, cold extremities, Raynaud's syndrome, venous stasis, phlebitis, arteritis)
Metabolic (overweight, obesity, non-insulin-dependent diabetes).
> Your antioxidant and anti-inflammatory defenses may not be effective enough.
This is because certain vitamins, minerals and fatty acids have to work to protect our cells against attack and to control inflammation.
Our body is able to produce some of these elements. Some such as omega 3 fatty acids are said to be essential because they can only be provided through food.
But there is a difference between what we put on the plate and what happens to our cells. The mechanisms of digestion, transport and assimilation can be lacking and therefore cause deficiencies or excesses: both equally harmful.
Biology is the only way to control these imbalances.
In addition, we are all different in terms of the ability to absorb a particular nutrient. There are people who respond well, that is to say that they will not need a large amount of nutrients to be assimilated. Others on the contrary will be poor responder and will need to add more for a beneficial effect.
Finally, biology makes it possible to verify the effectiveness of a treatment. For example, if I take this or that vitamin, does my level go up? And if it does not come back, then you have to ask yourself why and ask yourself the question of continuing to buy this supplement!
The same goes with diet. If I detect an omega 3 anti-inflammatory, anti-aggregating, hypogenolysis (which activates the melting of fat): does this make up for my deficits or does the problem come from assimilation?
What are the anti-oxidant and anti-inflammatory nutritional markers?
The Erythrocytic Fatty Acids Profile : this is the analysis of all the fatty acids that make up our cell membranes. There must be a balance between all these fatty acids. Indeed some have the properties of solidifying the membrane to protect it from attacks (intracellular viruses for example) others on the contrary to make it flexible to allow certain circulating cells (red blood cells for example) to twist to access the cells. the finest blood capillaries. The same goes with pro-inflammatory and anti-inflammatory fatty acids. Inflammation is a physiological reaction to get rid of dangerous elements. However, this inflammation must be controlled by real membrane firefighters to avoid conflagration.
As seen above, some of these fatty acids can be synthesized by the body but others must be provided by the diet or reflect the way of eating (cooking method for example).
SOD, GPX : this is the first line of defense. These enzymes neutralize free radicals as they appear in cells.
For their operation it requires several cofactors: copper and zinc, selenium and glutathione .
Finally, ferritin and transferrin : iron storage and transport proteins: exerts an indirect antioxidant effect by keeping this metal in a non-reactive state. Without these proteins the ferrous ion (Fe ++) would be transformed into an extremely reactive ferric ion (Fe +++).
Free radical scavengers: these are substances produced by the body or provided by food that stop the production of free radicals. Vitamin E, beta-carotene, lycopene, lutein and zeaxanthin (acting in the eyes, the biggest producer of oxidative stress in the body.
Note that carotenoids are liposoluble substances which means that their assimilation will only be possible in the presence of a fatty substance!
The apolipoproteins ApoA and ApoB are proteins responsible for transporting fats (triglycerides, cholesterol) in the blood. An ApoB / ApoA ratio is the second risk factor for coronary heart disease after smoking.
Lp (a) is an independent risk factor for the following pathologies: - Coronary diseases - Cerebrovascular diseases - Arteritis obliterans of the lower limbs - Restenosis after ocular angioplasty.
Ultrasensitive CRP : is the marker of invisible chronic inflammation (low grade) or significant localized inflammation (high grade). The production of excessive amounts of pro-inflammatory compounds promotes cancer development and / or progression by causing DNA damage, inhibiting the death of the infected cell, and stimulating cell migration and invasion.
Haptoglobulin is a marker of vascular inflammation.
A1GP is a high grade marker of inflammation and has a role in immune regulation.
Albumin and preallulmine are inflammation proteins very sensitive to deficiencies either by insufficient food intake or by excess consumption by inflammation or chronic infection, for example.
PINI Inflammatory and Nutritional Index : helps assess the inflammatory and antioxidant risk. This index is very useful before a surgical intervention for example.
Glutathione and Thioredoxin *: help regulate antioxidant defenses. An excess indicates the existence of a center of production of free radicals or an excess of external contribution. An insufficiency may be due to a deficit of synthesis or to overconsumption by prolonged or significant anti-radical defense.
IGF1 * is a protein related to growth hormone. It allows the development of atherosclerosis to be evaluated and its signaling has been found in colon cancer, in thyroid cancer and in breast cancer.
IGFPB3 * is the main transporter of IGF1. Its rate can be modified during hyperthyroidism, chronic renal failure, diabetes, breast, ovarian and prostate cancer.
The Homa and Quicki * indices are calculated from the plasma values of insulinemia (hormone that regulates the amount of sugar in the blood) and glycemia (amount of sugar in the blood) measured in a fasting individual. These indices make it possible to evaluate insulin resistance for HOMA and sensitivity to this hormone for QUICKI and to determine possible risk factors for type 2 diabetes.
Active B12 *: Mainly responsible for neurological or haematological disorders.
Vitamin D *: a vitamin deficiency has been demonstrated as a risk factor for breast cancer, gastric and colorectal cancer. In contrast, an excess of this vitamin is associated with an increased risk of prostate K.
Iodine * is involved in the composition of thyroid hormones ( T3 and T4 ).
But iodine is not only a substrate for thyroid hormones. It is also an essential element for the proper functioning of the thyroid gland (growth and trophicity).
* In the full balance sheet.